Research progress on the effects of platelet-rich fibrin on soft tissue repair and regeneration

Abstract

In recent years, with the development of tissue engineering, researches on the repair and regeneration of defected tissue have emerged in an endless stream. The issue of platelet-rich fibrin (PRF) for soft tissue repair and regeneration is a hot topic. PRF is a new biological material derived from autologous blood cells and rich in cell growth factors, which is known as the second generation of platelet concentrates. This article reviews the in vivo, in vitro and clinical studies of the effects of PRF on soft tissue repair and regeneration. Key words: Platelet-rich fibrin; Growth factors; Soft tissue; Regeneration