Research progress on quality assurance of genuine Chinese medicinal in Sichuan

Hua Luo,Qingmiao Li,Andong Yang,Luqi Huang,Qingmao Fang,Cheng Peng,Xiaobo Zhang,Hua Hua,Shunyuan Jiang,Yan Zhang,Yitao Wang,Lanping Guo,Peng Tan,Yiguan Zhang,Yi Zhao,Junning Zhao

doi:10.1186/s13020-021-00428-z

Abstract

The genuine Chinese medicinal (GCM), also known as Dao-di Herbs, is a synonym for high quality Chinese medicinal materials, which has been established in thousands of years of clinical practice and is a comprehensive standard for evaluating the quality of Chinese medicinal materials. The newest data from the Fourth National Survey of Chinese Medicinal Resources showed that Sichuan Province has 7290 types of Chinese medicine and 86 GCM, both ranking highly in China. The characteristics like diverse species, wide distribution, higher yield, and good quality are considered as advantages of geo-herbals grown in Sichuan. Resources guarantee and high-quality development of those medicine materials make a difference in local Chinese medicine quality promotion and Chinese medicine industry and technology development to serve the public's needs, assist targeted poverty alleviation, and strengthen ecological protection. This review aims to outline significant progress in the recent ten years regarding regionalization, germplasm resources, and quality evaluation around the quality assurance of GCM in Sichuan, China.

Highlights

Genuine Chinese medicinal (GCM), referring to highquality Chinese medicinal materials established by usage in clinical practice over thousands of years, functions as a comprehensive standard for Chinese medicine quality evaluation with historical and cultural attributes, and involves many influencing factors like genetics, environment, and production practice
In the past 10 years, based on the Fourth National Survey of Chinese Medicinal Resources (FNSCMR), Luo et al Chin Med (2021) 16:19 substantial progress has been made in research on production regionalization, germplasm resources, and quality evaluation, focusing on the quality assurance of Sichuan GCM
To sum up, this article focuses on explaining some critical technologies about the research and development of Sichuan GCM, such as genetic information and formation mechanism, quality biological evaluation, and cultivation of large varieties

Summary

Introduction

Genuine Chinese medicinal (GCM), referring to highquality Chinese medicinal materials established by usage in clinical practice over thousands of years, functions as a comprehensive standard for Chinese medicine quality evaluation with historical and cultural attributes, and involves many influencing factors like genetics, environment, and production practice. Ex Fr.) Karstand, Aconitum carmichaelii Debx., Gastrodia elata Bl., Ligusticum chuanxiong Hort., and Carthamus tinctorius L., etc., which number among the top in China. Based on these foundations, the seed-seedling bases and the germplasm resource base of Sichuan genuine Chinse medicine were built, and a dynamic monitoring system was established, while the observation points of CM were set up in key areas to dynamically monitor common and scarce species, and to realize the statistics aggregation and sharing of the census data from multiple sources. -Mazz, Gastrodia elata Bl., Psoralea corylifolia L., Rheum palmatum L., Phellodendron chinense Schneid., Eucommia ulmoides Oliv., Dipsacus asper Wall, ex Henry, Panax notoginseng (Burk.) F.

1–8 Croton tiglium L

Conclusion and perspectives