Research progress on optical biosensors for pathogenic bacteria detection

Abstract

Pathogenic bacteria bring serious harm to the human body and environment, and thus developing diverse detection methods for monitoring these pathogenic bacteria is still urgent. For this reason, it is very necessary to create a series of advanced optical biosensors to detect all kinds of pathogenic bacteria. Optical biosensors, here, are widely used for high sensitivity, excellent specificity, low cost, ease of handling, or other inherent advantages. In this paper, two classic optical biosensors, including colorimetric biosensors and fluorescence biosensors, are outlined in the field of pathogenic bacteria detection. In details, for the detection of pathogenic bacteria in colorimetric biosensors, colorimetry is divided into two categories based on plate and solution. To detect pathogenic bacteria in fluorescence biosensors, different biosensors are summarized, where a large number of fluorescent materials are used to create different fluorescence biosensors. In a word, the progress and limitation of both colorimetric biosensors and fluorescence biosensors in recent years are reviewed. The development direction of these optical biosensors has a broad prospect for the detection of pathogenic bacteria.