Abstract
Influenza virus, the causative agent of influenza, has characteristics of fast transmission and strong infectivity, posing a major threat to public health. Currently, with widely use of the first-line antiviral neuraminidase inhibitors, drug-resistant strains have appeared and brought difficulties to the precaution and treatment of influenza. This article reviews influenza virus structural characteristics, drug-resistance mechanisms, resistance situation and detection methods of drug-resistant virus strains, aiming to provide a reference for future research on influenza virus drug-resistance and clinical medication. Key words: Influenza A virus; Influenza B virus; Influenza C virus; Neuraminidase inhibitors; Drug-resistance; Mutation
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