Research progress of sumoylation in the regeneration of peripheral nerve injury

Abstract

Small ubiquitin-related modifiers (SUMOs) are discovered in recent years as a kind of important protein involved in the post-translational protein modification, and sumoylation plays an important role in a variety of biological processes in the human body. Peripheral nerve injuries are common in clinic, and the regeneration after injury is a rather complicated process. This article will review the latest research on the role of SUMO modification in the regeneration of peripheral nerve injury. Key words: Small ubiquitin-related modifier; Peripheral nerve injury; Neural repair and regeneration