Abstract
Knee osteoarthritis is a common and frequently occurring disease in clinic, and degeneration of articular cartilage is one of the main causes of this disease. Delaying cartilage degeneration and promoting cartilage repair are important ways to relieve pain and improve function. PRP is an autologous product derived from highly centrifugal blood, which contains a high concentration of effective factors, which can maintain tissue homeostasis and regulate the body's inflammation and coagulation. The product can regulate bone and blood vessel remodeling, inhibit chondrocyte apoptosis, inhibit inflammatory reaction and promote collagen synthesis by injection into the joint. PRP has unique advantages in the treatment of knee osteoarthritis, and has become one of the feasible methods for clinical treatment of KOA. Based on this, through this review, the author will elaborate the preparation of PRP, the mechanism of ACTION of KOA, the safety evaluation, the advantages of PRP and other treatment methods, and the combination of PRP and TRADITIONAL Chinese medicine in the treatment of knee osteoarthritis, aiming to provide new ideas, new methods and new methods for clinical diagnosis and treatment.
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