Research Progress of MicroRNA in Spinal Cord Injury

Abstract

Spinal cord injury (SCI) is a central nervous system disease with severe damage that causes partial or complete loss of movement and sensation below the injury segment, causing dysfunction. MicroRNAs (miRNAs) are a class of non-coding single-stranded RNA small molecules of approximately 18-25 nucleotides in length. Studies have shown that miRNAs play a regulatory role in the pathological process of spinal cord injury, which will provide a new target for the treatment of SCI. This article reviews the expression changes of microRNAs after spinal cord injury and the possible mechanisms of action in pathological processes.