Methylprednisolone in Spinal Cord Injury: The Possible Mechanism of Action

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Journal of NeurotraumaVol. 7, No. 3 Methylprednisolone in Spinal Cord Injury: The Possible Mechanism of ActionCHUNG Y. HSU and MILAN R. DIMITRIJEVICCHUNG Y. HSUSearch for more papers by this author and MILAN R. DIMITRIJEVICSearch for more papers by this authorPublished Online:27 Mar 2009https://doi.org/10.1089/neu.1990.7.115AboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail FiguresReferencesRelatedDetailsCited byPharmacologic and Regenerative Cell Therapy for Spinal Cord Injury: WFNS Spine Committee RecommendationsNeurospine, Vol. 17, No. 4Effects of combined treatment of minocycline and methylprednisolone on the expression of tumor necrosis factor alpha and interleukine-6 in experimental spinal cord injury: a light and electron microscopic study22 June 2020 | Ultrastructural Pathology, Vol. 44, No. 3Biomaterials for local drug delivery in central nervous systemInternational Journal of Pharmaceutics, Vol. 560Biomaterials for Local, Controlled Drug Delivery to the Injured Spinal Cord10 May 2017 | Frontiers in Pharmacology, Vol. 8The Current Status of Neuroprotection for Spinal Cord Injury7 June 2017Evaluation of the Combination of Methylprednisolone and Tranilast after Spinal Cord Injury in Rat ModelsJournal of Korean Neurosurgical Society, Vol. 59, No. 4Combination of methylprednisolone and rosiglitazone promotes recovery of neurological function after spinal cord injuryNeural Regeneration Research, Vol. 11, No. 10Neuroprotective effects of rosuvastatin against traumatic spinal cord injury in ratsEuropean Journal of Pharmacology, Vol. 741Immune modulatory therapies for spinal cord injury – Past, present and futureExperimental Neurology, Vol. 258Mn (III) tetrakis (4-benzoic acid) porphyrin scavenges reactive species, reduces oxidative stress, and improves functional recovery after experimental spinal cord injury in rats: comparison with methylprednisolone1 March 2013 | BMC Neuroscience, Vol. 14, No. 1Atorvastatin prevents early apoptosis after thoracic spinal cord contusion injury and promotes locomotion recoveryNeuroscience Letters, Vol. 453, No. 1Methylprednisolone inhibits the expression of glial fibrillary acidic protein and chondroitin sulfate proteoglycans in reactivated astrocytesGlia, Vol. 56, No. 13Annexin A1 Reduces Inflammatory Reaction and Tissue Damage Through Inhibition of Phospholipase A2 Activation in Adult Rats Following Spinal Cord InjuryJournal of Neuropathology and Experimental Neurology, Vol. 66, No. 10Post-trauma Lipitor treatment prevents endothelial dysfunction, facilitates neuroprotection, and promotes locomotor recovery following spinal cord injury17 November 2006 | Journal of Neurochemistry, Vol. 101, No. 1Secondary degeneration reduced by inosine after spinal cord injury in rats29 November 2005 | Spinal Cord, Vol. 44, No. 7Upregulation of type I interleukin−1 receptor after traumatic spinal cord injury in adult rats3 February 2006 | Acta Neuropathologica, Vol. 111, No. 3Effect of combined treatment with methylprednisolone and soluble Nogo-66 receptor after rat spinal cord injuryEuropean Journal of Neuroscience, Vol. 22, No. 3Attenuation of acute inflammatory response by atorvastatin after spinal cord injury in ratsJournal of Neuroscience Research, Vol. 79, No. 3Effects of Methylprednisolone on the Neural Conduction of the Motor Evoked Potentials in Spinal Cord Injured RatsJournal of Korean Medical Science, Vol. 20, No. 1Inhibition of the nuclear factor—κB activation with pyrrolidine dithiocarbamate attenuating inflammation and oxidative stress after experimental spinal cord trauma in ratsJournal of Neurosurgery: Spine, Vol. 1, No. 3Upregulation of annexins I, II, and V after traumatic spinal cord injury in adult ratsJournal of Neuroscience Research, Vol. 77, No. 3Histologic Characterization of Acute Spinal Cord Injury Treated with Intravenous MethylprednisoloneJournal of Orthopaedic Trauma, Vol. 16, No. 3iNOS and Nitrotyrosine Expression After Spinal Cord Injury Jan Xu, Gyeong-Moon Kim, Shawei Chen, Ping Yan, S. 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HOGAN, and P.L. PEROT26 March 2009 | Journal of Neurotrauma, Vol. 9, No. 3The neuroprotective pharmacology of methylprednisoloneJournal of Neurosurgery, Vol. 76, No. 1The experimental basis for early pharmacological intervention in spinal cord injurySpinal Cord, Vol. 29, No. 6Morphometric analysis of a model of spinal cord injury in guinea pigs, with behavioral evidence of delayed secondary pathologyJournal of the Neurological Sciences, Vol. 103, No. 2 Volume 7Issue 3Jan 1990 To cite this article:CHUNG Y. HSU and MILAN R. DIMITRIJEVIC.Methylprednisolone in Spinal Cord Injury: The Possible Mechanism of Action.Journal of Neurotrauma.Jan 1990.115-119.http://doi.org/10.1089/neu.1990.7.115Published in Volume: 7 Issue 3: March 27, 2009PDF download