Abstract
Intercellular adhesion molecules-1 (ICAM-1) is a member of immunoglobulin superfamily,which mediates leucocytes adhesion and rolling,and recruites leukocytes to the inflamed tissue,and promotes the release of the inflammatory mediators,and it plays an important role in acute lung injury and lung ischemia reperfusion injury.Recent researches have estimated that ICAM-1 is also involved in the pathogenesis of chronic obstructive pulmonary disease,metastasis of lung cancer,bronchial asthma,pulmonary fibrosis and other dieases.ICAM-1 is correlated with respiratory system diseases. Key words: Intercellular adhesion molecules-1 ; Macrophage differentiation antigen-1 ; Respiratory system diseases
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