Abstract

Natural protein-based hydrogels, which combine the biocompatibility, biodegradability, non-toxicity and adhesion of natural proteins, have been widely researched in the field of flexible and wearable sensors. In addition, the sensing capability of protein hydrogels can be elevated by improving their mechanical properties, electrical conductivity, self-healing adhesion and environmental stability. This paper reviews the research of protein-based hydrogels represented by silk fibroin, gelatin and keratin in flexible wearable sensors. Firstly, the preparation mechanism of these three proteins was introduced. Subsequently, we summarized the performance optimization strategies of protein-based hydrogels. Then, the application of protein-based hydrogels in flexible and wearable sensors is discussed. Finally, we summarized and prospected the recent research, which provided reference for the future relevant researchers.

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