Research progress of changes in thyroid function in short stature children both before and after therapy

Abstract

Short stature refers to the individual of the same race, gender and age, whose height is lower than the average height for about 2 standard deviations or under the 3rd percentile in the similar living environment.Its etiology mainly includes growth hormone deficiency, hypothyroidism, idiopathic short stature, Turner syndrome and so on.Short stature can be treated in childhood with recombinant human growth hormone (rhGH). Clinical evidence suggests that doctors should pay attention to thyroid hormone levels before and after rhGH therapy, so that they can offer thyroxine timely and maintain normal thyroid function for the children with hypothyroidism, which can improve the efficacy of rhGH in children with short stature. Key words: Short stature; Recombinant human growth hormone; Thyroid function