Abstract

Angiopoietin(Ang)is a secreted endothelial cell specific growth factor.Ang 2 levels in the body increase in bloodstream during infection.Studies have demonstrated that Ang 2 is a potential therapeutic target in sepsis.This paper reviews the biological function of Ang 2-Tie2 and Ang 2 inhibitors for a potential role of sepsis treatment. Key words: Sepsis; Ang1; Ang2; Tie2; Inflammation

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