Abstract

Neural development is a complex process.Its development is affected by a variety of molecular signals such as signals from intestinal microorganisms.Recent animal research showed that microorganisms play an important role in neurogenesis, myelination, microglial cell maturation and formation of blood-brain barrier, and the regulation of animal behavior from many aspects.This article reviewed the impact of prenatal and postnatal gut microbes on the development and function of the nervous system, and the relationship between gut microbes and autism spectrum disorder as well. Key words: Intestinal microflora; Autism spectrum disorder; Neurogenesis

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