Research on retrobulbar hemodynamics in senile patients with ischemic ophthalmopathy measured by color Doppler ultrasound

Abstract

Objective To investigate the retrobulbar hemodynamic changes in elderly patients with ischemic ophthalmopathy(IOP). Methods Three groups of 35 elderly unilateral IOP(n=35 patients), 32 elderly normal eye(n=32 volunteers)and 30 non-elderly normal eye(n=30 volunteers)were recruited in our hospital for the IOP or not, for elderly(aged≥60)or not(aged <60). The peak systolic velocity(PSV), end-diastolic velocity(EDV), resistance index(RI), color Doppler blood stream spectrum form and arm-retinal circulation time(A-RCT)in both ophthalmic artery(OA)and central retinal artery(CRA)were measured on three groups by color Doppler flow imaging(CDFI)and fundus fluorescein angiography(FFA). Results Compared with elderly normal eye group, or with non-elderly normal eye group, the elderly unilateral IOP group showed that PSV and EDV of both OA and CRA were decreased, RI was increased, CD blood stream spectrum form was changed and A-RCT was prolonged(all P 0.05), while CD blood stream spectrum form was changed(P<0.05). Conclusions In the elderly unilateral IOP patients, PSV and EDV of both OA and CRA are decreased, RI is increased, blood stream spectrum form is changed, and A-RCT is prolonged.The color Doppler ultrasound-detected hemodynamic changes are displayed clearly so that CDFI can provide a reliable evidence for clinical diagnosis of IOP. Key words: Senile ischemic ophthalmopathy; Ultrasonography; Hemodynamics