Abstract
By spent researches is established, that the products from a composite material on a basis gypsum and sulfur do not include in the structure potentially dangerous for organism of the person and environment of connections of mercury, thallium, selenium, arsenic; are chemically stable and do not allocate in inducing air, water and acid of environment unstable of inorganic connections. By manufacture of products on air environment of a working zone can be allocated hydrogen sulphide and sulphureous anhydride, that requires the appropriate organization of labour of the workers with maintenance of a premise by compulsory ventilation and measures of fire-prevention safety.
 Toxicological and hygienic studies of powdered sulfur gypsum material in case of cutaneous admission (50% vaseline emulsion) allowed to establish the following: after the first application of the paste, no visible changes were observed on the skin of animals. After ten applications in 2/3 of the experimental animals, pale pink erythema was observed throughout the paste application area. With further applications, the intensity of skin hyperemia did not increase. The resulting changes can be classified as a moderately pronounced skin irritating effect of powdered sulfur gypsum material.
 Analysis of the information obtained during the formulation of basophil degranulation reactions and specific agglomeration of blood leukocytes of guinea pigs sensitized with powdered sulfur gypsum material indicates the absence of statistically significant changes in the parameters of the studied reactions in animals of the experimental and control groups. This gives grounds for concluding that sulfur gypsum materials do not possess allergenic activity.
 Based on the conclusion of the Chief Sanitary Doctor of Ukraine, a composite material based on gypsum and sulfur is recommended for the manufacture of tiles that can be used in the construction of buildings of “B” and “V” groups (industrial and public buildings).
Highlights
Toxicological and hygienic studies of powdered sulfur gypsum material in case of cutaneous admission (50 % vaseline emulsion) allowed to establish the following: after the first application of the paste, no visible changes were observed on the skin of animals
After ten applications in 2/3 of the experimental animals, pale pink erythema was observed throughout the paste application area
Based on the conclusion of the Chief Sanitary Doctor of Ukraine, a composite material based on gypsum and sulfur is recommended for the manufacture of tiles that can be used in the construction of buildings of “B” and “V” groups
Summary
Связанных с токсикологической безопасностью производства и эксплуатации серогипсовых изделий, были проведены исследования совместно с Киевским НИИ общей и коммунальной гигиены. В задачу исследования входило решение следующих вопросов: изучение химического состава исследуемых материалов, исследование химической стабильности материалов в побуждающих воздушной и водной средах, а также при воздействии кислотных дождей; санитарно-технические исследования характеристик воздуха рабочей зоны при производстве серогипсовых изделий; токсико-гигиенические исследования серогипсовых материалов. Основную опасность воздействия на человека и окружающую среду при изготовлении серогипсовых изделий представляют газы H2S, SO2, пары серы и серная пыль. Пары серы при охлаждении конденсируются и превращаются в мелкодисперсную пыль. Предельно допустимая концентрация для воздуха рабочей зоны составляет 6 мг/м3. При ингаляционном пути поступления пылевидной серы в концентрациях 8...10 мг/м3 в организм наблюдается снижение ферментативной активности крови, развитие гипохронной анемии, лейкоанемии. При длительном воздействии на организм сероводород вызывает катары верхних дыхательных путей и расстройство пищеварения. Сера и сероводород не обладают эффектом отдаленных последствий для организма (концерогенным, терапогенным и эмбриотоксичным действием)
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