Research of the osseointegration and saucerization process in bone regeneration for dental implants: a concise systematic review

Abstract

​Introduction: In the context of implantology, bone regeneration is a science that aims to recover bone elevation for dental implants, with its main focus being the stomatognathic system. The treatment of oral rehabilitation with implants obtained a substantial evolution through the concept of osseointegration. A physiological process of peri-implant bone remodeling was observed during numerous investigations related to osseointegration and implantology. And, specific immune cells such as macrophages play a crucial role in the dynamics of osseointegration. Objective: to present the main approaches and clinical results on the process of bone regeneration, osseointegration, and saucerization in the implantology scenario through a systematic review of the literature. Methods: The present study followed a systematic review model, following the rules of systematic review – PRISMA. The search strategy was performed in the PubMed, Cochrane Library, Web of Science and Scopus, and Google Scholar databases. The quality of the studies was based on the GRADE instrument and the risk of bias was analyzed according to the Cochrane instrument. Results and Conclusion: The total of 156 articles were found. A total of 74 articles were fully evaluated and 20 were included in this study. Considering the Cochrane tool for risk of bias, the overall assessment resulted in 50 studies that were excluded with a high risk of bias (studies with a small sample size). Also, 12 studies were excluded because they did not meet the GRADE. Based on the objective of the present study, it was concluded that bone saucerization around osseointegrated implants represents a fundamental process for dental implant success, and with a controlled immunological process.