Research of outcome and risk factors of patients with traumatic brain injury occurred cerebral infarction

Abstract

Objective To evaluate the outcome and risk factors of patients with traumatic brain injury(TBI) occurred post-traumatic cerebral infarction(PTCI). Methods Four hundred and eight patients with TBI were selected, including 28 PTCI patients. The clinical data were retrospectively analyzed. Single factor analysis was used to analyzed the possible factors of PTCI, Multivariate analysis was used to analyzed the risk factors of PTCI. Results Twenty-eight cases(6.9%) had PTCI. Univariate analysis showed that the risk factors of PTCI were hypotension, intracranial infection, type of brain injury, initial GCS score and the use of hemostatic agents(P<0.05). Multivariate logistic regression analysis showed that low initial GCS score, herniation, brain contusion, and hypotension was independently associated with the occurrence of PTCI (all P<0.05). PTCI patients with severe disability (78.6% vs. 28.4%, P<0.01) and mortality (10.7% vs. 2.4%, P=0.012) were significantly higher than than those in non PTCI patients. Conclusions The low initial GCS score, herniation, brain contusion, hypotension are risk factors for TBI patients occurred PTCI, PTCI prompted poor prognosis. Key words: Traumatic brain injury; Cerebral infarction; Risk factors