Research of Lipid Metabolism Disorders in Female Combatants

Abstract

The objective: to find out the peculiarities of stress-induced changes in lipid metabolism indicators in women who have experienced concussion during combat operations. Study the state and morphostructure of adipose tissue. To analyze the relationship between lipid metabolism disorders and changes in reproductive health of female combatants. Materials and methods. The research was conducted at the Department of Obstetrics, Gynecology and Reproductology of the Ukrainian State Institute of Reproductology of the Shupyk National Healthcare University. 118 women participated in the study. Group I consisted of examination data of women who suffered concussion during combat operations with PTSD, group II – control, it consisted of healthy women. Average age of women who participated in hostilities and suffered contusion 27.08±4.23 years. Results. The influence of stress factors associated with military service in women servicemen on the development of lipid metabolism disorders is obvious. In the main group (118 women), blood cholesterol levels were significantly higher than in the control group. In parallel, a very low level of anti-atherogenic lipoprotein fractions was detected. Lipid metabolism in women who experienced concussion during combat with PTS was characterized by a high frequency of hyperlipidemia of types IIa and IIb, higher serum concentrations of atherogenic lipids fractions (CL, CL-LDL) and low anti-atherogenic fractions (CL-HDL), which were observed in all age subgroups and progressed with age. Conclusions. As a result of lipid metabolic disorders, the prerequisites for the development of hyperproliferative diseases of the female reproductive system, early and severe atherosclerosis are created.