Abstract
High-dose intravenous gamma globulin (2 g/kg) combined with oral aspirin is currently considered as standard strategy for Kawasaki disease(KD) in initial treatment.However, there are still 15%-25% of KD patients with no response to the treatment, thus leading to persistent fever, or even further damage of the coronary arteries.International literature have also mentioned other methods of treatment, such as corticosteroids, TNF-α blockade, lyclosporin, IL-1 receptor blockade, methotrexate, anti-CD20 rituximab, plasma exchange.But fixed standard for non-reactive gamma globulin require for further treatment. Key words: Kawasaki disease; Intravenous gamma globulin resistant; Glucocorticosteroid; Infliximab
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