Abstract

More than 100 years ago, a link was discovered between oral infections, tooth extractions, and cardiovascular disease (infective endocarditis) [1], and by the mid-20th century the practice of routinely prescribing antibiotics to prevent endocarditis prior to invasive dental procedures appeared [2]. In the last two decades, oral infections have again been considered a cause of systemic disease, with particular attention focused on their association with periodontal disease (PO) and atherosclerotic vascular disease (AZS) [3, 4].

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