Abstract
Copyright: © 2014 Lu J. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Currently, the discovery of Compounds induced Pluripotent Stem Cells (CiPSCs) and the Stimulus-Triggered Acquisition of Pluripotency (STAP) cells are rocking the field of stem cells [1].
Highlights
The discovery of Compounds induced Pluripotent Stem Cells (CiPSCs) and the Stimulus-Triggered Acquisition of Pluripotency (STAP) cells are rocking the field of stem cells [1]
Because of the ethic issues and potential xenograft rejection problems of human embryonic stem cells (ESCs), it is very hard for the derivatives of human ESCs to go directly towards clinical application
In 2006, Yamanaka group first showed a way of reprogramming mouse skin cells into pluripotent stem cells via defined transcription factors, which is a ground breakthrough in the stem cell field [5]
Summary
The discovery of Compounds induced Pluripotent Stem Cells (CiPSCs) and the Stimulus-Triggered Acquisition of Pluripotency (STAP) cells are rocking the field of stem cells [1]. In 1981, the first embryonic stem cells (ESCs) were first derived from mouse embryos by two groups respectively [2,3]. In 1998, a breakthrough occurred when Thomson group first developed a technique to isolate and grow human ESCs in cell culture [4].
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