Reproductive Organs Preserving Radical Cystectomy in Females

Abstract

Objectives: Classic radical cystectomy in females involves anterior exenteration for the treatment of invasive urothelial cancer. Pathological features of reproductive organs removed during exenteration were evaluated to determine the incidence of malignant pathology in these organs and need for removal. Methods: Case records of 26 females who underwent radical cystectomy with urinary diversion from January 1993 to December 2002 were reviewed. We reviewed preoperative, operative and pathological findings in these patients. Results: Median patient age was 46 years (range 17–64). Gynecologic organs were available for pathological examination in 26 patients. Invasive urothelial carcinoma involving uterus was identified in 1 specimen with invasion suspected preoperatively on computerized tomography and intraoperatively. Conclusions: Preserving reproductive organs in modified radical cystectomy is feasible in a carefully selected group of young women without jeopardizing the oncological basis of the operation.