Abstract
Malaria is still on the rise and affecting millions each year. The main reason is the development of resistance against the existing treatments and the requirement of the new regimen. Various areas in Southeast Asia have shown adverse health complications due to drug resistance. The transmission of malaria takes place through the Anopheles mosquito, and it is treated by antimalarial drugs that intercept the parasite's actions at different stages of its life cycle. Resistance to most drugs occurs due to genomic changes, which help the parasite survive against antimalarial drugs. It can be prevented by timely diagnosis and effective dose surveillance. No vaccine has been developed yet. Whereas newer treatments and approaches are underway.
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