Abstract
The Western Canadian Gastrointestinal Cancer Consensus Conference (WC-5) convened virtually on 10 February 2021. The WC-5 is an interactive multidisciplinary conference attended by health care professionals from across Western Canada (British Columbia, Alberta, Saskatchewan, and Manitoba) who are involved in the care of patients with gastrointestinal cancer. Surgical, medical, and radiation oncologists; pathologists; radiologists; and allied health care professionals participated in presentation and discussion sessions for the purpose of developing the recommendations presented here. This consensus statement addresses current issues in the management of hepatocellular cancer (HCC). Recommendations have been made for the transition from local to systemic therapy and the optimal sequencing of systemic regimens in the management of HCC.
Highlights
The mechanism of action of SIRT is the targeted delivery of radioactive compounds via the hepatic artery branches [13]. This is in contrast to transarterial chemoembolization (TACE), where there is a focused delivery of chemotherapy, and at the same time, an occlusion of small arterioles feeding the tumor
The treatment for hepatocellular carcinoma (HCC) is very often dictated by underlying liver disease. It is usually diagnosed in patients with chronic liver disease and treatment options depend on liver reserves, most commonly assessed by the Child–Turcotte– Pugh score
No standard therapy existed for advanced hepatocellular cancer (HCC) until 2008, when the landmark SHARP trial was reported [28] and firmly established sorafenib as the standard of care
Summary
The Western Canadian Gastrointestinal Cancer Consensus Conference welcomes medical oncologists, radiation oncologists, surgical oncologists, pathologists, radiologists, gastroenterologists, and allied health professionals from Western Canada who are involved in the care of patients with gastrointestinal malignancies (Table 1)
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