Abstract
The TMA Precision Health Clinical Decision Support system is a commercially available software platform focused on the confirmation of a precision diagnosis and generation of a personalized care plan to rapidly deliver therapeutic optionality and improve quality of life for rare and complex disease patients. For this study, we worked with our partners in Medellin, Colombia to evaluate the efficacy of the platform in identifying previously unexplored modes of care within a small sample population of adult patients suffering from a diverse set of rare diseases. Although challenges were encountered during the curation of data from multiple sources, personalized care plans and medication options were identified successfully for 94% of cases, suggesting a high level of impact for deployment at scale.
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