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Abstract

We really appreciate the comments regarding the differences between ethnicities, as Tan and associates indicated. Ethnicity should be taken into consideration depending on the working place; and, as the authors reflect, there are important differences between Chinese and white populations. Choroidal thickness and volume have been established in young adults, as well as the accuracy of the measurements performed by enhanced-depth imaging spectral-domain optical coherence tomography. It has been reported that choroidal thickness in healthy adults decreases with age, level of myopia, and axial length. 1 Sanchez-Cano A. Orduna E. Segura F. et al. Choroidal thickness and volume in healthy young white adults and the relationships between them and axial length, ammetropy and sex. Am J Ophthalmol. 2014; 158: 574-583.e1 Abstract Full Text Full Text PDF PubMed Scopus (82) Google Scholar , 2 Margolis R. Spaide R.F. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am J Ophthalmol. 2009; 147: 811-815 Abstract Full Text Full Text PDF PubMed Scopus (1031) Google Scholar , 3 Barteselli G. Chhablani J. El-Emam S. et al. Choroidal volume variations with age, axial length, and sex in healthy subjects: A three-dimensional analysis. Ophthalmology. 2012; 119: 2572-2578 Abstract Full Text Full Text PDF PubMed Scopus (156) Google Scholar Regarding differences between the regions across the posterior pole, choroidal thickness has been found to be thinnest in the nasal and inferior regions. The mean subfoveal choroidal thickness in healthy adults has been reported to be different among ethnic groups. 1 Sanchez-Cano A. Orduna E. Segura F. et al. Choroidal thickness and volume in healthy young white adults and the relationships between them and axial length, ammetropy and sex. Am J Ophthalmol. 2014; 158: 574-583.e1 Abstract Full Text Full Text PDF PubMed Scopus (82) Google Scholar , 2 Margolis R. Spaide R.F. A pilot study of enhanced depth imaging optical coherence tomography of the choroid in normal eyes. Am J Ophthalmol. 2009; 147: 811-815 Abstract Full Text Full Text PDF PubMed Scopus (1031) Google Scholar , 3 Barteselli G. Chhablani J. El-Emam S. et al. Choroidal volume variations with age, axial length, and sex in healthy subjects: A three-dimensional analysis. Ophthalmology. 2012; 119: 2572-2578 Abstract Full Text Full Text PDF PubMed Scopus (156) Google Scholar , 4 Ikuno Y. Kawaguchi K. Nouchi T. Yasuno Y. Choroidal thickness in healthy Japanese subjects. Invest Ophthalmol Vis Sci. 2010; 51: 2173-2176 Crossref PubMed Scopus (500) Google Scholar , 5 Ding X. Li J. Zeng J. et al. Choroidal thickness in healthy Chinese subjects. Invest Ophthalmol Vis Sci. 2011; 52: 9555-9560 Crossref PubMed Scopus (219) Google Scholar Although healthy adults' choroidal thickness has been thoroughly investigated, studies on choroidal thickness in pathologic or pediatric populations are limited. Normative databases are still needed, and we are working on it. Choroidal Thickness and Volume in Healthy Young White Adults and the Relationships Between Them and Axial Length, Ammetropy and SexAmerican Journal of OphthalmologyVol. 159Issue 4PreviewWe read with interest the article by Sanchez-Cano and associates,1 which evaluated choroidal thickness in young adults using enhanced-depth imaging spectral-domain optical coherence tomography (OCT), and we agree that a normative database is important to facilitate comparisons of choroidal thicknesses among patients with ocular disease. It is increasingly evident that the choroid plays important roles both in normal physiology and in ocular diseases,2–4 the study of which will be greatly facilitated by enhanced-depth imaging and the new swept-source OCT devices. Full-Text PDF