Abstract

The two olefinic backbone replacements III and IV were synthesized and incorporated into oligonucleotides. The hybridization properties of the modified oligonucleotides to DNA and RNA complements and conformational analyses of III and IV are compared to the corresponding amide modifications I and II.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.