Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)

Koen P Rovers ,Maarten J Deenen ,Iris Van ’T Erve ,Clément J.r Huysentruyt ,Emma Wassenaar ,Maartje Los,Alexander Constantinides,Rudaba Tajzai,Remond J.a Fijneman ,Onno Kranenburg,Robin J Lurvink ,Harm J Scholten ,Max J Lahaye ,Jacobus W A Burger ,Simon W Nienhuijs ,Marinus J Wiezer ,Thomas J.m Kootstra ,Geert Jan Creemers ,Joost Nederend,Djamila Boerma,Anna M.j Thijs ,Ignace H J T De Hingh

doi:10.1136/bmjopen-2019-030408

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC)

Koen P Rovers , Maarten J Deenen + Show 20 more

Open Access

https://doi.org/10.1136/bmjopen-2019-030408

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Journal: BMJ open	Publication Date: Jul 1, 2019
Citations: 20	License type: open-access

Affiliation: Radboud University Nijmegen, Catharina Ziekenhuis, Netherlands Cancer Institute-Antoni van Leeuwenhoek Hospital, St. Antonius Ziekenhuis, University Medical Center Utrecht, Cancer Genomics Centre, Oncode Institute, Maastricht University

#Unresectable Peritoneal Metastases #Colorectal Peritoneal Metastases + Show 8 more

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Abstract

IntroductionRepetitive electrostatic pressurised intraperitoneal aerosol chemotherapy with oxaliplatin (ePIPAC-OX) is offered as a palliative treatment option for patients with isolated unresectable colorectal peritoneal metastases (PM) in several centres worldwide. However,...

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