Abstract
Incidence rate of articular cartilage injury is increasing. As cartilage is a highly differentiated tissue without direct supply of blood or nerve and has limited regeneration potential after injury, treatment of cartilage injury still poses a major challenge for both patients and orthopedic surgeons. Mesenchymal stem cells (MSCs) are a class of pluripotent stem cells with potent proliferative capacity and chondrogenic ability, and are being used to repair articular cartilage injury through tissue engineering. The aim of this article is to provide a comprehensive review of MSC transplantation for the treatment of articular cartilage injury. Key words: Cartilage; Repair; Mesenchymal stem cells; Tissue engineering
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