Abstract
The effect of temperature sensitive (ts) mutations in five early function genes on the sensitivity of phage T4D to ultraviolet (UV) light was determined. Temperature sensitive mutations in genes 30, 43, and 47 were found to increase the sensitivity of T4D to ultraviolet light. Mutations in genes 45 and 56 did not alter UV sensitivity. Gene 30 has been identified as the structural gene for polynucleotide ligase (Fareed and Richardson, 1967); gene 43 codes for DNA polymerase (deWaard et al., 1965; Warner and Barnes, 1966); mutants in gene 47 are unable to degrade the host chromosome (Wiberg, 1966) and are probably defective in a deoxyribonuclease. Deoxycytidine triphosphatase is the enzyme specified by gene 56 (Wiberg, 1967); and the product of gene 45 has not been identified.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Cold Spring Harbor symposia on quantitative biology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
