Abstract

The renormalization group (RG) method of Chen, Goldenfeld, Oono et al. offers a comprehensive approach to formally computing asymptotic expansions of the solutions to singular perturbation problems. A renormalization group formalism developed recently for the Michaelis–Menten (MM) model is extended to competitive systems. We will first revisit the singular perturbation analysis for the standard quasi‐steady‐state approximation (sQSSA) of enzyme‐substrate‐inhibitor kinetics. Our result shows that the RG method leads to a new prediction for the concentrations of substrate, inhibitor, and complexes, which can reproduce or surpass the results of matched asymptotics.

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