Renal responses of the Chilean toad, Calyptocephalella caudiverbera, and the mud puppy, Necturus maculosus, to mesotocin

Abstract

Intravenous injections of mesotocin resulted in increased urine production in the Chilean toad, Calyptocephalella caudiverbera, and the mud puppy, Necturus maculosus. At low doses, the diuretic responses increase with the doses of hormone administered, but at high doses the diuretic response is considerably reduced. These findings confirm those reported previously for the bullfrog ( P.K.T. Pang and W.H. Sawyer, 1978, Amer. J. Physiol. 235(2), F151–F155). However, this is the first time that such data are reported for an aquatic toad and an aquatic urodele.