Abstract
Hypophysectomized male mud puppies ( Necturus maculosus) adapted to fresh water exhibited hyponatremia and hypocalcemia which were alleviated by ovine prolactin injections. However, if the animals were adapted to 0.6% sodium chloride solution, hypophysectomy produced hypocalcemia but not hyponatremia. These data suggest that mud puppy pituitary glands are specifically involved in calcium regulation in addition to their involvement in sodium regulation. Injection of ovine prolactin produced hypercalcemia and hypernatremia in intact mud puppies adapted to 0.6% sodium chloride solution containing high levels of calcium. However, the hormone had no significant effect on plasma calcium or sodium values in animals adapted to low-sodium fresh water with or without addition of calcium.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
