Abstract
When rats were given cadmium in drinking water in low doses for their lifetimes, and when such animals became hypertensive, renal arterial and arteriolar lesions, and glomerular changes characteristic of the hypertensive state were usually found. Control rats or those given lead, chromium, arsenic, germanium or tin rarely exhibited these lesions. The pathological changes associated with cadmium hypertension in rats is indistinguishable from those accompanying benign hypertension from other causes.
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