Abstract

BackgroundNo measure of childhood behaviour has been validated in Uganda despite the documented risks to behaviour. Cerebral malaria in children poses a great risk to their behaviour, however behavioural outcomes after cerebral malaria have not been described in children. This study examined the reliability of the Luganda version of the Child Behaviour Checklist (CBCL) and described the behavioural outcomes of cerebral malaria in Ugandan children.MethodsThe CBCL was administered to parents of 64 children aged 7 to 16 years participating in a trial to improve cognitive functioning after cerebral malaria. These children were assigned to the treatment or control group. The CBCL parent ratings were completed for the children at baseline and nine weeks later. The CBCL was translated into Luganda, a local language, prior to its use. Baseline scores were used to calculate internal consistency using Cronbach Alpha. Correlations between the first and second scores of the control group were used to determine test-retest reliability. Multicultural norms for the CBCL were used to identify children with behavioural problems of clinical significance.ResultsThe test-retest reliability and internal consistency of the Internalising scales were 0.64 and 0.66 respectively; 0.74 and 0.78 for the Externalising scale and 0.67 and 0.83 for Total Problems. Withdrawn/Depressed (15.6%), Thought Problems (12.5%), Aggressive Behaviour (9.4%) and Oppositional Defiant Behaviour (9.4%) were the commonly reported problems.ConclusionThe Luganda version of the CBCL is a fairly reliable measure of behavioural problems in Ugandan children. Depressive and thought problems are likely behavioural outcomes of cerebral malaria in children. Further work in children with psychiatric diagnoses is required to test its validity in a clinical setting.

Highlights

  • No measure of childhood behaviour has been validated in Uganda despite the documented risks to behaviour

  • We present a study carried out in Ugandan children to examine the reliability of the Luganda version of the Child Behaviour Checklist (CBCL) and to document the behavioural problems after cerebral malaria as measured by the CBCL

  • Study participants were a cohort of cerebral malaria survivors earlier admitted to the hospital who participated in studies examining the cognitive and neurological outcomes of the disease with testing at 0, 3, 6, and 24 months [11,25]

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Summary

Introduction

No measure of childhood behaviour has been validated in Uganda despite the documented risks to behaviour. Cerebral malaria in children poses a great risk to their behaviour, behavioural outcomes after cerebral malaria have not been described in children. The other studies that have assessed the behavioural outcomes of cerebral malaria are either cases studies [13,14] with limited ability to generalise, or do not describe the behavioural functions affected [15,16]. Documentation of the behavioural problems after cerebral malaria can highlight what problems to assess for in survivors and to help develop appropriate interventions for affected children. Despite the lack of documentation of behavioural problems, the burden of cerebral malaria on children's development is evident with estimates putting the number of children with cognitive and behavioural problems after cerebral malaria at over 200,000 per year [11,16]

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