Abstract

may present in its most severe forms. 2,5,6,8 Despite a vigorous program of malaria control in the Kingdom of Saudi Arabia, the infection is still endemic in the southwestern area of the country. 9 As a result of continued preventive measures, the epidemiology of the disease may be changing, and the proportion of nonimmune individuals may increase. Furthermore, the emergence of chloroquine-resistant malaria in the neighboring country of Yemen has a major implication for the Gizan population. 2,4 The frequency and clinical outcome of severe malaria may provide useful, albeit indirect, information on the emergence of antimalarial drug resistance in this region. We describe the clinicopathologic profile and mortality in patients treated for severe malaria in King Fahad Central Hospital (KFCH), Gizan, Saudi Arabia.

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