Abstract
Dual metal regulated bottom gate top contact structured Organic Thin Film Transistor based biosensor (Bio-OTFT) for recognition of breast cancer cell lines along with the non-tumorigenic epithelial cell line is presented here. A feasible fabrication scheme for Bio-OTFT has been demonstrated. Repulsive steric hindrance (RSH) consideration inside the cavity zone directs more practical and realistic sensing mechanisms. The insightful electrostatic analysis regarding electric field, energy band diagram, transfer characteristics (IDS-VGS), and transconductance (gm) has been described. Alteration of the dielectric constant (k) of these cancerous and healthy cell lines stated the recognition scheme in this reported Bio-OTFT. The efficiency of the recommended model has been assessed thoroughly with the reported OTFT literatures. The sensitivity is examined respecting drain current (IDS) in (A/μm), gm in (μS/μm), threshold voltage (VTH) in Voltage and sub-threshold swing (SS) in (mV/dec) and reaches to the maximum value of 2.3 × 108, 1.85 × 1010, 0.68, and 0.08 for T-47D cell line at VGS = −1.25 V. The recommended model thus suggests an enormous reliability and possibility for biosensing purposes.
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