Abstract
Changes in intraoral pH can cause changes in the chemical decomposition and surface properties of treated resin-based pits and fissure sealants (sealant). The purpose of this study is to evaluate the release of bisphenol A (BPA) from sealants under three different pH conditions over time. The test specimen was applied with 6 sealants 5 mg each on a glass plate (10 × 10 mm) and photopolymerized. The samples were immersed for 10 min, 1 h, and 24 h in solutions of pH 3.0, 6.5, and 10.0 at 37 °C. BPA release was measured using a gas chromatography-mass spectrometer. A statistical analysis was performed by two-way ANOVA and one-way ANOVA to verify the effect of pH conditions and time on BPA release. The BPA concentration in the pH 3.0 group was higher at all points than with pH 6.5 and pH 10.0 (p < 0.05), and gradually increased over time (p < 0.05). As a result, it was confirmed that low pH negatively influences BPA release. Therefore, frequent exposure to low pH due to the consumption of various beverages after sealant treatment can negatively affect the sealant’s chemical stability in the oral cavity.
Highlights
Dental pits and fissure sealants are among the most commonly used materials to prevent tooth decay in children and adolescents [1,2,3,4]
The purpose of this study is to evaluate the release of bisphenol A (BPA) from sealants in 3 conditions of pH over time
In the pH 6.5 and pH 10.0 groups, the BPA concentration was higher at 24 h (0.28, 0.52 ppm)
Summary
Dental pits and fissure sealants (sealant) are among the most commonly used materials to prevent tooth decay in children and adolescents [1,2,3,4]. Sealants consist mainly of bis-GMA, bis-EMA, and bis-EMA monomers containing bisphenol A (BPA, CAS number: 80-05-7) [5,6]. BPA may exist as an impurity if chemical synthesis is not completed in the process of preparing the dental sealant based on monomers such as bis-GMA, or if the synthesis reset does not reach stoichiometric completion. In 1996, Olea et al [5] reported that leakage of BPA from dental sealants to patient saliva increased concerns about the potential estrogenicity of dental materials. Another study by Fung et al [7] argued that BPA released from tooth sealants might be absorbed or present in undetectable amounts in the systemic circulation
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
