Abstract
To report the case of a patient with bipolar affective disorder (BPD) in psychiatric care, who was diagnosed three times with Neuroleptic Malignant Syndrome by different antipsychotics (NMS). A 57-year-old female patient with previous diagnosis of BD was admitted to the hospital with fever, muscle stiffness, tremors, behavioral changes, lowering of consciousness level, increased CPK and leukocytosis, which were not clarified by another medical condition, then suspected of Neuroleptic Malignant Syndrome. The use of antipsychotics is essential for several psychiatric disorders, such as mania, personality disorders and dementia in general, and the onset of NMS is unpredictable. It is concluded that a depth knowledge of the disease is necessary for early diagnosis and treatment, which will result a better prognosis.
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