Abstract
Cervical vestibular evoked myogenic potential (cVEMP) and cochlear hydrops analysis masking procedure (CHAMP) have both shown sensitivity in identifying Meniere’s disease. However none of the previous reports have compared the two tests for their relative efficacy in identifying Meniere’s disease. Hence the present study aimed to compare the efficiency of cVEMP and CHAMP in evaluating Meniere’s disease. The study included 58 individuals with unilateral definite Meniere’s disease and an equal number of age and gender matched healthy individuals. cVEMP corresponding to 500 Hz tone burst was recorded from ipsilateral sternocleidomastoid muscle and CHAMP was acquired from the conventional electrode sites for single channel auditory brainstem response recording using a default protocol of the Biologic Navigator Pro evoked potential system. Both cVEMP and CHAMP showed statistically significant differences between the groups (P<0.05). The receiver operating curves revealed 100% sensitivity and specificity for CHAMP as against 70.7% sensitivity and 100% specificity for cVEMP in identifying Meniere’s disease. Therefore, CHAMP appears to be the test of choice provided the degree of hearing loss does not exceed a moderate degree. cVEMP could be used for all degrees of hearing losses, but with slight constraint on the sensitivity.
Highlights
Meniere’s disease is a progressive idiopathic disorder of the inner ear, which may result in degeneration of cochlear and vestibular hair cells
The control group consisted of 58 healthy individuals (30 males and 28 females) in the age range of 20 to 50 years with normal audiovestibular system which was ascertained by normal results on pure-tone audiometry, type “A” tympanogram with acoustic reflex threshold within 100 dB HL at octave frequencies from 500 to 2000 Hz, presence of otoacoustic emissions, and indication of no retrocochlear pathology on auditory brainstem responses
In order to fulfill the objectives of the present study, 58 individuals with Meniere’s disease were compared with an equal number of age and gender matched healthy individuals on Cervical vestibular evoked myogenic potential (cVEMP) and cochlear hydrops analysis masking procedure (CHAMP)
Summary
Meniere’s disease is a progressive idiopathic disorder of the inner ear, which may result in degeneration of cochlear and vestibular hair cells. It was first described by Prosper Meniere in 1861 and since it has been noted as one of the most common disorders of the vestibular system [1]. Other researchers suspect pathologies of the stria vascularis to be responsible for the symptom complex in Meniere’s disease [7]. Still others believe it to be a possible autoimmune disorder [8]. Irrespective of the beliefs regarding the causative factors, the etiology of Meniere’s symptoms has been shown to be an abnormal increase in endolymph volumes in the inner ear [9,10,11,12]
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
