Abstract
A series of O-alkyl-O-arylphenylphosphonothioates were synthesized and their partition coefficients and the corresponding R F values were determined by thin-layer chromatography (TLC) with different solvent systems and by reversed-phase and polyamide layer techniques. Gas-liquid chromatographic (GLC) relative retention times were determined on different stationary phases with increasing polarity. Partition between n-octanol and water was determined using a GLC detection technique. The partition data and chromatographic properties were compared and correlated with physico-chemical linear free energy parameters for electronic, hydrophobic and steric forces. GLC partitioning is influenced by electronic and steric forces, whereas TLC partitioning is influenced by electronic and hydrophobic forces, depending on the polarity of the mobile phase.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
