Relationship of erythrocyte sedimentation rate with the activity of prolidase and liver enzyme in serum of patients with rheumatoid arthritis

Abstract

Abstract The study was conducted on 55 samples with 35 samples afflicted with rheumatoid arthritis disease. The samples were distributed as 15 patient females, 20 patient males and 20 as a control group (healthy) with no disease. The control group were distributed to 10 females and 10 males and their ages ranged from 10 to 80 years old. The samples were collected from Samarra General Hospital and the city's outpatient clinics. After collecting blood from healthy and patient groups, the samples were separated by means of a centrifuge, the biochemical parameter: prolidase enzyme, liver enzymes, including AST, ALT, ALP and the red blood deposition rate were measured. The results of CRP and RF appear to be positive in patient with rheumatoid arthritis compared to healthy people who are negative. The results of the current research showed a significant increase in the rate of red blood cell deposition in the blood serum of people with rheumatoid arthritis compared to healthy people, and a significant decrease of the prolidase enzyme in the blood serum of people with rheumatoid arthritis compared to healthy people, and the results showed that a significant increase in the level of liver enzymes represented by (AST, ALT, ALP) in the blood serum of people with rheumatoid arthritis compared to healthy people. The results showed a negative correlation between the rate of Erythrocyte Sedimentation rate and the activity of prolidase enzyme and AST, in addition to a positive correlation between the rate of erythrocyte sedimentation and the activity of ALP and ALT enzyme in the blood serum of people with rheumatoid arthritis.