Abstract
: To study the relationship of diabetic retinopathy with systemic complications of diabetes.: Study was conducted on 310 diabetic patients attending to Narayana medical college ophthalmology opd in Nellore between August 2017and June 2018. Patients are categorized into five groups based on the duration and severity of DR into No DR, Mild NPDR, ModerateNPDR, Severe NPDR, PDR according to the ETDRS classification. All the above patients evaluated clinically, and required investigations were done for the presence of systemic complications like nephropathy, neuropathy, cardiovascular, cerebrovascular, and diabetic foot. The relation between the duration of diabetes mellitus and stage of diabetic retinopathy and also with systemic complications assessed. A total of 310 diabetic patients with a mean age of 56.5 + 11.8 years and males 211(31.7%) and females99(31.7%). Prevalence of Diabetic retinopathy was 108(34.8%) of which mild NPDR44(41.9%), moderate NPDR35(34.5%), severe NPDR 19(18.3%)and PDR10(11.4%). A significant association (P<0.001) was observed between the duration of diabetes and the presence and severity of diabetic retinopathy. The overall prevalence of nephropathy, neuropathy, diabetic foot, CVS, CAD was 52.6%and they were significantly (p<0.05) more common in patients with DR (64.8%) as compared to those with no DR (43.5%) and complications increased with severity of retinopathy.
Highlights
Diabetic retinopathy is a microvascular complication affecting the eyes of both type 1 and type 2 diabetes mellitus. 1 Diabetic retinopathy is 4.8% of the 37 million cases of blindness throughout the world,[2] according to the World Health Organisation
Diabetic retinopathy was present in 108 (34.8%) patients, of which 44 (41.9%) patients had mild NPDR, 35(34.5%) had moderate NPDR, 19(18.3%) had severe NPDR, and 10(11.4%) patients were of PDR
PN (27.7%) is the most common systemic complication associated with diabetes followed by CKD (23.1%), coronary artery disease (CAD) (13.8%), DF(12.9%), CVA(9.25%)
Summary
Diabetic retinopathy is a microvascular complication affecting the eyes of both type 1 and type 2 diabetes mellitus. 1 Diabetic retinopathy is 4.8% of the 37 million cases of blindness throughout the world,[2] according to the World Health Organisation. Diabetic retinopathy is a microvascular complication affecting the eyes of both type 1 and type 2 diabetes mellitus. 1 Diabetic retinopathy is 4.8% of the 37 million cases of blindness throughout the world,[2] according to the World Health Organisation. The associated metabolic deregulation causes subsequent pathophysiological changes in multiple organ systems, and the risk of complications increases with disease duration. After 20 years, some grade of retinopathy develops in nearly 99 percent of patients of type 1 and about 60 percent of type 2 diabetes mellitus. 25 to 40 percent of patients with DM type I, and 20-30 percent of DM type II develop diabetic nephropathy.[4] About 60-70% of people with diabetes have some form of neuropathy.[5]
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Indian Journal of Clinical and Experimental Ophthalmology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
