Abstract

The aim of this study was to determine the relationship between the severity of hypertension and renal impairment in preeclampsia. This study was conducted on 92 diagnosed cases of mild (n=42) and severe (n=50) preeclampsia patients from August 2010 to July 2011. All the patients were almost identical in terms of age and socioeconomic status. The results of the study showed that the mean serum creatinine and uric acid levels were significantly high in severe preeclampsia patient compared to mild preeclampsia and both systolic and diastolic blood pressures had the positive and significant effects on the serum creatinine and uric acid levels. In conclusion, impairment of renal function has the positive and significant relationship with the severity of blood pressure in the preeclamptic patient.

Highlights

  • Preeclampsia is the most common hypertensive disorder during pregnancy and has the greatest effect on the maternal and infant outcome.[1]

  • Mean serum creatinine was significantly higher in severely preeclamptic women than the mild preeclamptic women which is similar to another study done.[18]

  • The study was done on 40 preeclamptic patients (18 diabetic women) (DM-PRW) and 22 without diabetes (PRW) and 20 normotensive pregnant women (8 with gestatational diabetes and rest 12 were healthy preeclamptic women) and the control group consisting of 20 healthy non-pregnant women

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Summary

Introduction

Preeclampsia is the most common hypertensive disorder during pregnancy and has the greatest effect on the maternal and infant outcome.[1]. Despite the advancement in the field of medicine, preeclampsia/eclampsia still remains the third leading cause of maternal mortality.[3] Though preeclampsia/eclampsia is a largely preventable condition and the incidence is decreasing in the developed countries. It occurs in about 6% of the general population.[4] such cases still possess a great problem in the developing countries like Bangladesh

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