Relationship between serum levels of creatinine,urea nitrogen and lung image changes in uremic patients

Abstract

Objective To explore the relationship between serum creatinine （ Scr ） , blood urea nitrogen （ BUN） and lung image changes in uremic patients .Methods According to the chest CT ,X-ray and related findings , 256 patients with uremia were divided into 84 cases of uremia （ uremic lung group ） and non-uremic lung 172 cases （ non-uremic lung group ） .The chest CT and X-ray examination ,Scr and BUN levels were observed .Results Uremic lung group had five types of image findings,including alveolar edema （67.86%）,pulmonary interstitial edema （16.67%）,pulmonary congestion syndrome（8.33%）,pleural effusion（4.76%） and pulmonary interstitial fibrosis （2.38%）.The Scr[（1 145.6 ±236.4）μmol/L]and BUN [（38.9 ±6.1）mmol/L]levels in uremic lung group were significantly higher than those in the non-uremic lung group[（905.3 ±138.9）μmol/L,（23.8 ±5.6）mmol/L]（t=8.128,4.782,all P〈0.05）.Conclusion The image of uremic lung is mainly pulmonary edema ,and radiological and pathological changes are closely related with Scr and BUN levels . Key words: Uremia; Lung; Tomography,X-ray computed; X-ray film; Kidney function tests