Relationship between serum homocysteine and vascular stenosis degree of cerebral infarction diagnosed by CTA

Abstract

Objective To analyze the relationship between serum homocysteine (Hcy) level and vascular stenosis degree of cerebral infarction diagnosed by CT angiography (CTA). Methods 378 patients with cerebral infarction treated at our hospital from February, 2016 to February, 2017 were enrolled into this study and were given CTA and serum Hcy test. The CTA results were counted; and the relationship between Hcy and vascular stenosis degree of cerebral infarction diagnosed by CTA was analyzed. Results There were 341 cases of vascular stenosis or occlusion detected by CTA in the 378 patients, with a detection rate of 90.21%. 85 cases got light vascular stenosis, 91 cases moderate, 103 cases severe, and 62 cases occlusion. 25 cases had vascular stenosis or occlusion in extracranial artery, 86 cases in intracranial artery, and 230 cases in intracranial and extracranial arteries. The determination of offending vessels showed that the extracranial artery stenosis or occlusion mainly happened in the initial part of intracranial artery; the intracranial part was mainly in middle cerebral artery and intracranial artery siphon; and the intracranial and extracranial part was mainly in the initial part of intracranial artery, middle cerebral artery and intracranial artery siphon and intracranial vertebral artery. The more serious the vascular stenosis degree was, the higher the Hcy level and the incidence of hyperhomocysteinemia were (P<0.05). Conclusions Serum Hcy level positively correlates with vascular stenosis degree of cerebral infarction diagnosed by CTA. Serum Hcy level may have a certain value in determining vascular stenosis degree. Key words: Serum homocysteine; CT angiography; Vascular stenosis; Cerebral infarction; Relationship analysis