Abstract
Molar incisor hypomineralization (MIH) affects the first permanent molars and permanent incisors whose formative embryological process develops around birth and the first year of life. This study’s main objective is to assess the relationship between MIH, on the one hand, with the administration during childbirth of epidural bupivacaine, intramuscular meperidine with haloperidol, synthetic intravenous oxytocin, and prostaglandins such as dinoprostone vaginally, and on the other hand, with suffered pathologies during the first year of life. Cross-sectional retrospective study was carried out on 111 children who attended dental check-ups. Oral examination was carried out to determine MIH involvement. Data on the administration of medications during delivery and the illnesses suffered by the children in the first year of life were taken from the hospital records. Significant relationship with Pearson's chi-square was found between the presence of MIH and the administration of meperidine with haloperidol intramuscularly and the vaginal administration of dinoprostone during labour. Also in children who have suffered serious infections and those who have received antibiotics in early childhood. In recent years there has been a growing trend in many countries to medicalize childbirth even above what the World Health Organization recommends. Some of the drugs used in these protocols could be involved in the appearance of dental mineralization alterations of the MIH type and this would help to explain the increase in its prevalence.
Highlights
Molar incisor hypomineralization (MIH) affects the first permanent molars and permanent incisors whose formative embryological process develops around birth and the first year of life
Molar incisor hypomineralization (MIH) is an anomaly of dental development that is associated with causes of systemic origin, with the involvement of one to four permanent first molars and often permanent incisors
Deliveries are increasingly medicated and instrumented[17], for this reason, we have considered it important to study what medications had been administered to both children and mothers at the time of delivery since the first permanent molars show their first signs of mineralization at the tips of the cusps around or shortly after b irth[11]
Summary
Molar incisor hypomineralization (MIH) affects the first permanent molars and permanent incisors whose formative embryological process develops around birth and the first year of life. The enamel is weakened and when the teeth come into contact during chewing it tends to give way, producing cracks and cavities. Prevalence of MIH has increased in recent years, in countries where there are a high number of inductions to labour. Etiology of this pathology remains unclear, and it is likely a multifactorial cause, with a higher prevalence in children whose mothers had complications during pregnancy and delivery. At present, both pregnancy and especially childbirth have become frequently medicated processes according to various protocols
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