Relationship between high-density lipoprotein and high-sensitivity cardial troponin T in elderly

Abstract

Objective To High-density lipoprotein cholesterol (HDL-C) has the protective effect on cardiovascular system and low levels of HDL-C are considered as risk factors of cardiovascular diseases independent of low-density lipoprotein cholesterol. High-sensitivity cardial troponin T (hs-cTnT) was preferred marker of myocardial damage and predictor of cardiovascular outcomes. There was nearly no study exploring the relationship between HDL-C and hs-cTnT levels in community elderly. Methods To evaluate the correlation between HDL-C and hs-cTnT levels in a Chinese community population of 885 elderly, univariate analyses and multivariable linear regression analysis were performed. Results There were 367 males (41.5%) and 518 females (58.5%) in all. Their age ranged form 60 to 96 years, with a mean age of (69.2±6.36) years. In univariate analyses, HDL-C levels were negatively related to hs-cTnT levels (r=-0.06, P=0.008). After adjustment for some confounding factors, hs-cTnT levels were independently associated with different groups of HDL-C levels divided by the quartiles in community elderly. Conclusions In Chinese community elderly, we found that HDL-C levels have the independent associations with myocardial damage. Key words: HDL-C; hs-cTnT; Elderly; Cardiovascular system; Multivariate analysis