Abstract
The relation between agranular reticulum and glycogen was studied in hepatic cells of female rats. Prolonged fasting of nonadrenalectomized rats did hot result ins complete liver glycogen depletion, whereas in adrenalectomized rats this could be accomplished within a few hours of fasting. In nonadrenalectomized rats a marked development of agranular reticulum associated with glycogen was found, whereas in adrenalectomized rats no such marked development of agranular reticulum was seen during glycogen depletion. Early glycogen restoration in glycogen-depleted liver cells of adrenalectomized rats was brought about 2-4 hr after the injection of 1 dose of cortisone or ½-1 hr after the injection of glucose. Early restoration of glycogen was accompanied and even preceded by a marked development of tubular agranular reticulum. A probable role of this organelle in glycogen synthesis and breakdown is discussed. High resolution autoradiography of tritium-labeled glucose incorporation offered some further illustration on the process of glycogen formation.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
