Abstract
Background Diffuse interstitial fibrosis is a common end point in heart failure from multiple etiologies. The post contrast T1 time, extracellular volume (ECV) and partition coefficient (l) of gadolinium-based contrast media have been used to estimate expansion of myocardial interstitial space, as a surrogate of interstitial fibrosis. The aim of the study was to explore the relationship between T1-based estimates of interstitial expansion and both right (RV) and left (LV) ventricular functional parameters in pulmonary hypertension (PH).
Highlights
Diffuse interstitial fibrosis is a common end point in heart failure from multiple etiologies
The aim of the study was to explore the relationship between T1-based estimates of interstitial expansion and both right (RV) and left (LV) ventricular functional parameters in pulmonary hypertension (PH)
Phase contrast velocity encoded cine imaging was obtained perpendicular to the main pulmonary artery for RV stroke volume assessment
Summary
Diffuse interstitial fibrosis is a common end point in heart failure from multiple etiologies. The post contrast T1 time, extracellular volume (ECV) and partition coefficient (l) of gadolinium-based contrast media have been used to estimate expansion of myocardial interstitial space, as a surrogate of interstitial fibrosis. The aim of the study was to explore the relationship between T1-based estimates of interstitial expansion and both right (RV) and left (LV) ventricular functional parameters in pulmonary hypertension (PH)
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